Notification of transaction by Person Discharging Managerial Responsibilities ("PDMR")

 _________________________________________________________________________
|1 |Details of the person discharging managerial responsibilities/person  |
|  |closely associated                                                    |
|__|______________________________________________________________________|
|a)|Name                          |Paul Atherley                          |
|__|______________________________|_______________________________________|
|2 |Reason for the notification                                           |
|__|______________________________________________________________________|
|a)|Position/status               |Chairman                               |
|__|______________________________|_______________________________________|
|b)|Initial notification/Amendment|Initial notification                   |
|__|______________________________|_______________________________________|
|3 |Details of the issuer, emission allowance market participant, auction |
|  |platform, auctioneer or auction monitor                               |
|__|______________________________________________________________________|
|a)|Name                          |Pensana Plc                            |
|__|______________________________|_______________________________________|
|b)|LEI                           |213800H4QP6T9499RU64                   |
|__|______________________________|_______________________________________|
|  |Details of the transaction(s): section to be repeated for (i) each    |
|4 |type of instrument; (ii) each type of transaction; (iii) each date;   |
|  |and (iv) each place where transactions have been conducted            |
|__|______________________________________________________________________|
|a)|Description of the financial  |Ordinary Shares of £0.001 each         |
|  |instrument, type of instrument|                                       |
|__|______________________________|_______________________________________|
|  |Identification code           |GB00BKM0ZJ18                           |
|__|______________________________|_______________________________________|
|  |                              |Admission and issue of shares as       |
|  |                              |settlement of an advance to Pensana Plc|
|b)|Nature of the transaction     |under GBP 2 million directors loan     |
|  |                              |facility as more fully announced on 23 |
|  |                              |July 2024.                             |
|__|______________________________|_______________________________________|
|  |                              |Price: £0.1666                         |
|c)|Price(s) and volume(s)        |                                       |
|  |                              |Volume: 1,500,000                      |
|__|______________________________|_______________________________________|
|  |                              |Aggregated volume: 1,500,000           |
|d)|Aggregated information        |                                       |
|  |                              |Aggregated Price: £0.1666              |
|__|______________________________|_______________________________________|
|e)|Date of the transaction       |23 July 2024                           |
|__|______________________________|_______________________________________|
|f)|Place of the transaction      |London Stock Exchange                  |
|__|______________________________|_______________________________________|