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About the company
Aprea Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on precision oncology through synthetic lethality. The Company's advanced synthetic lethality product candidate is ATRN-119, a clinical-stage small molecule inhibitor of ataxia telangiectasia and Rad3-related (ATR) a kinase that plays a critical role in DNA damage response (DDR). ATR and Checkpoint Kinase 1 are critical DDR kinases that prevent the collapse of replication forks into DNA double-strand breaks. It has completed all IND enabling studies for its oral, small molecule WEE1 inhibitor, APR-1051, and received United States Food and Drug Administration (FDA) clearance of its IND. It has an early-stage program that is in the lead optimization stage, for an undisclosed DDR target. The Company is evaluating potential combination opportunities within its pipeline, including research on the combination of ATRN-119 and APR-1051 that is supported by a Phase II SBIR grant from the National Cancer Institute.
- Revenue in USD (TTM)1.31m
- Net income in USD-13.51m
- Incorporated2019
- Employees7.00
- LocationAprea Therapeutics Inc3805 OLD EASTON ROADDOYLESTOWN 18902United StatesUSA
- Phone+1 (617) 463-9385
- Fax+1 (302) 655-5049
- Websitehttps://www.aprea.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Microbot Medical Inc | 0.00 | -10.44m | 16.83m | 22.00 | -- | 2.69 | -- | -- | -0.81 | -0.81 | 0.00 | 0.3793 | 0.00 | -- | -- | 0.00 | -113.94 | -53.28 | -133.34 | -62.65 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 18.44 | -- | -31.76 | -- |
| Synlogic Inc | 3.17m | -56.16m | 16.92m | 6.00 | -- | 1.06 | -- | 5.34 | -7.24 | -7.24 | 0.3549 | 1.37 | 0.0628 | -- | -- | 528,333.30 | -111.31 | -40.57 | -131.17 | -43.82 | -- | -- | -1,771.74 | -3,245.93 | -- | -- | 0.00 | -- | 185.68 | 5.99 | 13.40 | -- | -48.05 | -- |
| Kairos Pharma Ltd | 0.00 | -2.01m | 17.21m | -- | -- | -- | -- | -- | -0.1562 | -0.1562 | 0.00 | -0.2067 | 0.00 | -- | -- | -- | -199.80 | -- | -- | -- | -- | -- | -- | -- | -- | -15.58 | -- | -- | -- | -- | -72.57 | -- | -- | -- |
| Lyra Therapeutics Inc | 1.82m | -101.39m | 17.52m | 87.00 | -- | 0.5655 | -- | 9.62 | -1.61 | -1.61 | 0.0294 | 0.4733 | 0.0165 | -- | -- | 20,681.82 | -92.07 | -58.01 | -108.51 | -68.69 | -- | -- | -5,570.88 | -6,235.31 | -- | -- | 0.00 | -- | 14.31 | 4.60 | -13.39 | -- | 95.14 | -- |
| Kazia Therapeutics Ltd (ADR) | 14.84k | -13.47m | 17.76m | 12.00 | -- | 1.65 | -- | 1,196.48 | -8.17 | -8.17 | 0.0081 | 3.48 | 0.0007 | -- | 73.97 | -- | -63.98 | -46.35 | -82.39 | -54.75 | -- | -- | -90,714.45 | -497.17 | -- | -- | 0.1297 | -- | 979.43 | -28.31 | 18.19 | -- | -- | -- |
| Cocrystal Pharma Inc | 0.00 | -17.93m | 17.91m | 12.00 | -- | 1.03 | -- | -- | -1.76 | -1.76 | 0.00 | 1.71 | 0.00 | -- | -- | 0.00 | -61.98 | -50.94 | -66.88 | -52.77 | -- | -- | -- | -1,501.78 | -- | -- | 0.00 | -- | -- | -- | 53.69 | -- | 33.34 | -- |
| Finch Therapeutics Group Inc | 0.00 | -14.17m | 18.95m | 18.00 | -- | 1.33 | -- | -- | -8.82 | -8.82 | 0.00 | 8.86 | 0.00 | -- | -- | -- | -25.20 | -- | -28.80 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -87.57 | -- | 34.80 | -- | -- | -- |
| Aprea Therapeutics Inc | 1.31m | -13.51m | 19.28m | 7.00 | -- | 0.8791 | -- | 14.71 | -2.81 | -2.81 | 0.2646 | 4.28 | 0.0498 | -- | -- | 187,262.90 | -51.30 | -68.66 | -60.22 | -77.19 | -- | -- | -1,030.42 | -42,112.84 | -- | -- | 0.00 | -- | -- | -- | 87.32 | -- | 90.61 | -- |
| Calidi Biotherapeutics Inc | 0.00 | -24.92m | 19.62m | 41.00 | -- | -- | -- | -- | -5.41 | -5.41 | 0.00 | -1.82 | 0.00 | -- | -- | 0.00 | -279.89 | -- | -- | -- | -- | -- | -- | -- | -- | -27.58 | -- | -- | -100.00 | -- | -14.90 | -- | -- | -- |
| Unity Biotechnology Inc | 0.00 | -19.05m | 19.71m | 19.00 | -- | 1.39 | -- | -- | -1.14 | -1.14 | 0.00 | 0.8394 | 0.00 | -- | -- | 0.00 | -32.73 | -47.21 | -38.49 | -53.51 | -- | -- | -- | -6,395.92 | -- | -- | 0.00 | -- | -100.00 | -- | 10.36 | -- | -61.28 | -- |
| Goldenwell Biotech Inc | 940.00 | -137.11k | 19.80m | -- | -- | 5,169.71 | -- | 21,063.83 | -0.0014 | -0.0014 | 0.00001 | 0.00004 | 0.0048 | 0.0031 | -- | -- | -69.82 | -- | -70.29 | -- | 42.55 | -- | -14,586.17 | -- | 21.43 | -- | 0.00 | -- | -95.10 | -- | 88.13 | -- | -- | -- |
| NanoViricides Inc | 0.00 | -8.29m | 20.08m | 7.00 | -- | 1.65 | -- | -- | -0.698 | -0.698 | 0.00 | 0.8722 | 0.00 | -- | -- | 0.00 | -55.81 | -43.88 | -59.61 | -46.26 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 3.43 | -- | 16.23 | -- |
| MEI Pharma Inc | 65.30m | 17.78m | 20.26m | 28.00 | 1.14 | 0.6134 | 1.12 | 0.3102 | 2.67 | 2.67 | 9.80 | 4.96 | 0.8052 | -- | 1,536.40 | 2,332,036.00 | 21.92 | -21.09 | 26.64 | -23.99 | -- | -- | 27.23 | -72.23 | -- | -- | 0.00 | -- | 33.76 | 67.75 | 155.84 | -- | -49.68 | -- |
| Cognition Therapeutics Inc | 0.00 | -31.08m | 20.27m | 25.00 | -- | 0.8804 | -- | -- | -0.9317 | -0.9317 | 0.00 | 0.5736 | 0.00 | -- | -- | 0.00 | -79.36 | -- | -104.49 | -- | -- | -- | -- | -- | -- | -263.29 | 0.00 | -- | -- | -- | -20.52 | -- | -- | -- |
| Promis Neurosciences Inc | 0.00 | -12.20m | 21.54m | 6.00 | -- | -- | -- | -- | -0.6924 | -0.6924 | 0.00 | -0.1201 | 0.00 | -- | -- | 0.00 | -839.15 | -144.28 | -- | -262.23 | -- | -- | -- | -2,271,047.00 | -- | -- | -- | -- | -- | -- | 26.85 | -- | -- | -- |
Data as of Nov 08 2024. Currency figures normalised to Aprea Therapeutics Inc's reporting currency: US Dollar USD
40.87%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| AIGH Capital Management LLCas of 30 Jun 2024 | 539.30k | 9.93% |
| Stonepine Capital Management LLCas of 07 Oct 2024 | 365.44k | 6.73% |
| Sio Capital Management LLCas of 30 Jun 2024 | 276.60k | 5.09% |
| Sphera Funds Management Ltd.as of 30 Jun 2024 | 270.00k | 4.97% |
| Nantahala Capital Management LLCas of 30 Jun 2024 | 205.76k | 3.79% |
| Altium Capital Management LPas of 30 Jun 2024 | 137.20k | 2.53% |
| DAFNA Capital Management LLCas of 30 Jun 2024 | 137.17k | 2.53% |
| Exome Asset Management LLCas of 30 Jun 2024 | 137.17k | 2.53% |
| The Vanguard Group, Inc.as of 30 Jun 2024 | 115.84k | 2.13% |
| Geode Capital Management LLCas of 30 Jun 2024 | 35.67k | 0.66% |
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Data from 30 Jun 2024 - 30 Jun 2024Source: FactSet Research Systems Inc.
