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About the company
Amicus Therapeutics, Inc. is a biotechnology company, which is focused on discovering, developing, and delivering novel medicines for rare diseases. Its two marketed therapies are Galafold, the first oral monotherapy for people living with Fabry disease who have amenable genetic variants, and Pombiliti + Opfolda, a novel treatment designed to improve uptake of active enzyme into key disease relevant tissues for adults living with late-onset Pompe disease. As an orally administered monotherapy, Galafold is designed to bind to and stabilize an endogenous alpha-galactosidase A (alpha-Gal A) enzyme in those patients with genetic variants identified as amenable in a Good Laboratory Practice (GLP) cell-based amenability assay. Pombiliti + Opfolda consists of a uniquely engineered rhGAA enzyme, cipaglucosidase alfa-atga, with an optimized carbohydrate structure to enhance lysosomal uptake, administered in combination with miglustat that functions as an enzyme stabilizer.
- Revenue in USD (TTM)455.66m
- Net income in USD-119.54m
- Incorporated2002
- Employees517.00
- LocationAmicus Therapeutics Inc3675 Market StreetPHILADELPHIA 19104United StatesUSA
- Phone+1 (215) 921-7600
- Fax+1 (609) 662-2001
- Websitehttps://www.amicusrx.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PTC Therapeutics, Inc. | 900.45m | -479.52m | 2.73bn | 988.00 | -- | -- | -- | 3.03 | -6.32 | -6.32 | 11.84 | -12.75 | 0.5534 | 2.16 | 4.94 | 911,390.70 | -29.47 | -26.71 | -44.23 | -33.46 | 92.35 | 93.94 | -53.25 | -83.80 | 2.17 | -1.16 | 1.70 | -- | 34.20 | 28.78 | -12.09 | -- | 32.00 | -- |
| Celldex Therapeutics, Inc. | 8.30m | -150.22m | 2.77bn | 160.00 | -- | 3.41 | -- | 334.15 | -2.74 | -2.74 | 0.1481 | 12.28 | 0.0145 | -- | 10.05 | 51,887.50 | -26.24 | -29.65 | -27.27 | -31.42 | -- | -- | -1,809.40 | -1,747.94 | -- | -- | 0.00 | -- | 192.02 | -6.32 | -25.91 | -- | 17.46 | -- |
| Ideaya Biosciences Inc | 11.96m | -153.74m | 2.94bn | 124.00 | -- | 2.84 | -- | 245.46 | -2.18 | -2.18 | 0.1718 | 12.24 | 0.0159 | -- | 148.57 | 96,451.61 | -20.48 | -19.17 | -21.42 | -21.05 | -- | -- | -1,285.44 | -244.55 | -- | -- | 0.00 | -- | -54.08 | -- | -92.59 | -- | 6.75 | -- |
| Kymera Therapeutics Inc | 88.55m | -157.85m | 2.99bn | 181.00 | -- | 4.17 | -- | 33.78 | -2.41 | -2.41 | 1.36 | 11.12 | 0.1258 | -- | 30.40 | 473,529.40 | -22.42 | -23.03 | -24.45 | -27.64 | -- | -- | -178.27 | -207.82 | -- | -- | 0.0028 | -- | 67.84 | -- | 5.07 | -- | 91.01 | -- |
| Xenon Pharmaceuticals Inc | 0.00 | -199.06m | 3.04bn | 251.00 | -- | 3.59 | -- | -- | -2.74 | -2.74 | 0.00 | 11.15 | 0.00 | -- | -- | 0.00 | -25.38 | -20.71 | -26.37 | -21.81 | -- | -- | -- | -683.58 | -- | -- | 0.00 | -- | -100.00 | -- | -45.99 | -- | 61.77 | -- |
| Guardant Health Inc | 643.81m | -490.76m | 3.09bn | 1.78k | -- | -- | -- | 4.79 | -4.09 | -4.09 | 5.36 | -0.0131 | 0.3733 | 4.04 | 6.89 | 361,894.30 | -28.46 | -22.26 | -32.21 | -24.59 | 59.95 | 64.62 | -76.23 | -97.07 | 6.07 | -10.18 | 1.00 | -- | 25.45 | 44.14 | 26.76 | -- | 0.2786 | -- |
| Iovance Biotherapeutics Inc | 32.77m | -440.22m | 3.09bn | 557.00 | -- | 3.93 | -- | 94.19 | -1.68 | -1.68 | 0.1245 | 2.59 | 0.0381 | 2.40 | 2.07 | 58,836.63 | -51.14 | -51.47 | -57.20 | -57.56 | -37.43 | -- | -1,343.27 | -137,873.80 | 4.85 | -- | 0.0013 | -- | -- | -- | -12.16 | -- | 79.44 | -- |
| Apogee Therapeutics Inc | 0.00 | -118.49m | 3.12bn | 91.00 | -- | 3.91 | -- | -- | -2.25 | -2.25 | 0.00 | 13.65 | 0.00 | -- | -- | 0.00 | -25.44 | -- | -26.65 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -111.10 | -- | -- | -- |
| Amicus Therapeutics, Inc. | 455.66m | -119.54m | 3.24bn | 517.00 | -- | 24.40 | -- | 7.10 | -0.397 | -0.397 | 1.51 | 0.4471 | 0.6159 | 0.6948 | 6.12 | 881,344.30 | -16.16 | -30.65 | -20.75 | -36.55 | 89.88 | 88.94 | -26.23 | -86.10 | 2.26 | -0.6134 | 0.7459 | -- | 21.30 | 34.35 | 35.92 | -- | 3.36 | -- |
| Rhythm Pharmaceuticals Inc | 101.78m | -260.73m | 3.28bn | 226.00 | -- | 83.30 | -- | 32.22 | -4.37 | -4.37 | 1.71 | 2.94 | 0.2943 | 1.25 | 6.48 | 450,367.30 | -75.00 | -47.21 | -87.80 | -52.84 | 88.80 | -- | -254.88 | -681.38 | 6.31 | -- | 0.3765 | -- | 227.56 | -- | -1.97 | -- | -42.10 | -- |
| Alvotech SA | 308.73m | -618.38m | 3.34bn | 999.00 | -- | -- | -- | 10.81 | -2.65 | -2.65 | 1.28 | -2.27 | 0.312 | 1.80 | 3.66 | 309,038.00 | -62.49 | -- | -222.85 | -- | 48.79 | -- | -200.30 | -- | 0.1569 | -0.2323 | 2.04 | -- | 9.84 | -- | -7.43 | -- | -- | -- |
| MoonLake Immunotherapeutics | 0.00 | -54.80m | 3.39bn | 50.00 | -- | 6.41 | -- | -- | -0.9043 | -0.9043 | 0.00 | 8.28 | 0.00 | -- | -- | 0.00 | -11.08 | -- | -11.49 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 27.95 | -- | -- | -- |
| Dyne Therapeutics Inc | 0.00 | -257.60m | 3.45bn | 152.00 | -- | 4.44 | -- | -- | -3.58 | -3.58 | 0.00 | 7.74 | 0.00 | -- | -- | 0.00 | -47.82 | -52.81 | -50.15 | -57.45 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -40.36 | -- | 40.32 | -- |
| Biohaven Ltd | 0.00 | -746.61m | 3.72bn | 239.00 | -- | 9.48 | -- | -- | -9.15 | -9.15 | 0.00 | 4.16 | 0.00 | -- | -- | 0.00 | -137.07 | -- | -176.64 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | 28.43 | -- | -- | -- |
Data as of Sep 19 2024. Currency figures normalised to Amicus Therapeutics Inc's reporting currency: US Dollar USD
62.11%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| Perceptive Advisors LLCas of 30 Jun 2024 | 28.06m | 9.46% |
| The Vanguard Group, Inc.as of 30 Jun 2024 | 27.79m | 9.37% |
| Avoro Capital Advisor LLCas of 30 Jun 2024 | 27.40m | 9.24% |
| BlackRock Fund Advisorsas of 30 Jun 2024 | 21.43m | 7.23% |
| Wellington Management Co. LLPas of 30 Jun 2024 | 20.88m | 7.04% |
| Janus Henderson Investors US LLCas of 30 Jun 2024 | 13.11m | 4.42% |
| William Blair Investment Management LLCas of 30 Jun 2024 | 13.05m | 4.40% |
| SSgA Funds Management, Inc.as of 30 Jun 2024 | 11.02m | 3.72% |
| JPMorgan Investment Management, Inc.as of 30 Jun 2024 | 10.90m | 3.67% |
| Redmile Group LLCas of 30 Jun 2024 | 10.60m | 3.57% |
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Data from 30 Jun 2024 - 30 Jun 2024Source: FactSet Research Systems Inc.
