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About the company
Ionis Pharmaceuticals, Inc. is engaged in ribonucleic acid (RNA)-targeted therapeutics. The Company has five marketed medicines and a pipeline in neurology, cardiology, and other areas of high patient need. It has nine medicines in Phase III development and multiple additional medicines in early and mid-stage development. The Company’s products include SPINRAZA, QALSODY, WAINUA, TEGSEDI and WAYLIVRA. SPINRAZA is used for the treatment of patients with spinal muscular atrophy (SMA), a progressive, debilitating and often fatal genetic disease. QALSODY is an antisense medicine that is used for the treatment of adult patients with superoxide dismutase 1 amyotrophic lateral sclerosis (SOD1-ALS), a rare, neurodegenerative disorder that causes progressive loss of motor neurons leading to death. WAINUA is a self-administered subcutaneous LIgand-Conjugated Antisense (LICA) medicine used for the treatment of adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis (ATTRv-PN).
- Revenue in USD (TTM)813.46m
- Net income in USD-365.74m
- Incorporated1991
- Employees927.00
- LocationIonis Pharmaceuticals Inc2855 Gazelle CourtCARLSBAD 92010United StatesUSA
- Phone+1 (760) 931-9200
- Fax+1 (302) 655-5049
- Websitehttps://www.ionispharma.com/
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Peer analysis
Key Information
- Key Information
- Stock Performance
- Per Share Data
- Efficiency
- Management Effectiveness
- Profitability
- Financial Strength
- Growth Rates
| Company | Revenue (TTM) | Net income (TTM) | Market cap | Employees | Price/earnings (TTM) | Price/book value (MRQ) | Price/cash flow (TTM) | Price/sales (TTM) | EPS (excl. extraordinary items, TTM) | EPS (incl. extraordinary items, TTM) | Revenue per share (TTM) | Book value per share (MRQ) | Asset turnover (TTM) | Inventory turnover (TTM) | Receivables turnover (TTM) | Revenues per employee (TTM) | Return on avg assets (TTM) | Return on avg assets (5 yr avg) | Return on investment (TTM) | Return on investment (5 yr avg) | Gross margin (TTM) | Gross margin (5 yr avg) | Net profit margin (TTM) | Net Profit margin (5 yr avg) | Quick ratio (MRQ) | Interest coverage (TTM) | Total debt to capital (MRQ) | Payout ratio (5 yr avg) | Revenue (YOY change %) | Revenue (5 yr growth rate) | Net income (YOY change %) | Net income (5 yr growth rate) | Capital expenditure (5 yr growth rate) | Dividend (5 yr growth rate) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Arcellx Inc | 144.75m | -53.89m | 4.33bn | 130.00 | -- | 8.87 | -- | 29.91 | -1.05 | -1.05 | 2.84 | 9.08 | 0.2132 | -- | -- | 1,113,423.00 | -7.94 | -38.82 | -9.68 | -45.41 | -- | -- | -37.23 | -339.38 | -- | -- | 0.038 | -- | -- | -- | 62.53 | -- | 113.86 | -- |
| Denali Therapeutics Inc | 1.27m | -419.65m | 4.40bn | 364.00 | -- | 3.17 | -- | 3,475.74 | -2.85 | -2.85 | 0.0085 | 9.69 | 0.0009 | -- | -- | 2,847.19 | -29.89 | -14.98 | -31.50 | -17.71 | -- | -- | -33,121.86 | -104.50 | -- | -- | 0.00 | -- | 204.74 | 20.67 | 55.45 | -- | 30.70 | -- |
| Alkermes Plc | 1.51bn | 457.54m | 4.58bn | 2.10k | 10.41 | 3.60 | 9.00 | 3.04 | 2.67 | 1.69 | 8.78 | 7.74 | 0.6864 | 1.31 | 4.28 | 718,055.30 | 20.83 | 1.34 | 26.98 | 1.74 | 83.31 | 83.32 | 30.34 | 2.12 | 2.61 | -- | 0.184 | 0.00 | 49.61 | 8.74 | 1,665.99 | -- | -7.10 | -- |
| Madrigal Pharmaceuticals Inc | 14.64m | -510.45m | 5.06bn | 376.00 | -- | 5.90 | -- | 345.85 | -25.50 | -25.50 | 0.7351 | 39.50 | 0.0209 | -- | -- | 38,930.85 | -72.80 | -62.09 | -86.71 | -74.81 | 95.66 | -- | -3,487.13 | -- | 8.67 | -- | 0.1198 | -- | -- | -- | -26.50 | -- | 132.01 | -- |
| Krystal Biotech Inc | 166.23m | 105.94m | 5.25bn | 229.00 | 50.02 | 6.25 | 46.53 | 31.58 | 3.65 | 3.65 | 5.70 | 29.22 | 0.2076 | -- | -- | 725,908.30 | 13.23 | -11.50 | 14.07 | -12.01 | 93.07 | -- | 63.73 | -492.85 | 9.33 | -- | 0.00 | -- | -- | -- | 107.81 | -- | 39.49 | -- |
| Ultragenyx Pharmaceutical Inc | 481.30m | -585.12m | 5.32bn | 1.28k | -- | 12.29 | -- | 11.05 | -7.29 | -7.29 | 5.95 | 4.69 | 0.3286 | 1.81 | 5.45 | 377,196.70 | -39.94 | -33.35 | -48.51 | -38.30 | 87.15 | 93.13 | -121.57 | -154.71 | 3.39 | -- | 0.00 | -- | 19.52 | 53.18 | 14.25 | -- | 62.91 | -- |
| Blueprint Medicines Corp | 362.80m | -205.49m | 5.66bn | 638.00 | -- | 17.62 | -- | 15.60 | -3.42 | -3.42 | 5.85 | 5.07 | 0.3141 | 0.8694 | 5.88 | 553,887.00 | -17.79 | -29.92 | -21.66 | -34.06 | 96.19 | -- | -56.64 | -116.65 | 3.65 | -16.38 | 0.5471 | -- | 22.22 | 41.14 | 9.06 | -- | 4.85 | -- |
| Cytokinetics, Inc. | 3.13m | -545.28m | 6.58bn | 423.00 | -- | 60.57 | -- | 2,100.15 | -5.37 | -5.37 | 0.0309 | 0.9236 | 0.0027 | -- | 6.36 | 7,408.98 | -47.34 | -43.14 | -51.07 | -47.22 | -- | -- | -17,398.82 | -540.47 | -- | -12.85 | 0.8578 | -- | -92.04 | -24.89 | -35.30 | -- | 9.76 | -- |
| Ionis Pharmaceuticals Inc | 813.46m | -365.74m | 6.67bn | 927.00 | -- | 23.46 | -- | 8.20 | -2.53 | -2.53 | 5.63 | 1.81 | 0.2873 | 0.4264 | 29.47 | 877,517.80 | -12.92 | -6.30 | -14.43 | -7.44 | 98.58 | 98.75 | -44.96 | -21.23 | 7.51 | -- | 0.8288 | -- | 34.10 | 5.60 | -35.80 | -- | 11.83 | -- |
| Nuvalent Inc | 0.00 | -173.59m | 6.70bn | 115.00 | -- | 10.43 | -- | -- | -2.78 | -2.78 | 0.00 | 9.84 | 0.00 | -- | -- | 0.00 | -31.08 | -- | -32.81 | -- | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -54.20 | -- | -- | -- |
| Viking Therapeutics Inc | 0.00 | -96.75m | 7.14bn | 28.00 | -- | 7.75 | -- | -- | -0.9379 | -0.9379 | 0.00 | 8.31 | 0.00 | -- | -- | 0.00 | -14.36 | -21.91 | -14.78 | -23.04 | -- | -- | -- | -- | -- | -- | 0.00 | -- | -- | -- | -24.73 | -- | -- | -- |
| Revolution Medicines Inc | 742.00k | -519.21m | 7.36bn | 443.00 | -- | 4.51 | -- | 9,918.78 | -3.65 | -3.65 | 0.0051 | 9.77 | 0.0005 | -- | 0.5912 | 1,962.96 | -36.03 | -29.76 | -38.48 | -32.59 | -- | -- | -69,973.99 | -606.93 | -- | -- | 0.00 | -- | -67.27 | -10.50 | -75.46 | -- | 38.82 | -- |
| Exelixis Inc | 2.01bn | 349.99m | 7.65bn | 1.31k | 22.97 | 3.61 | 20.32 | 3.80 | 1.17 | 1.17 | 6.54 | 7.43 | 0.6809 | 3.23 | 6.40 | 1,537,386.00 | 11.83 | 8.86 | 13.38 | 9.91 | 96.06 | 96.30 | 17.38 | 15.43 | 4.21 | -- | 0.00 | 0.00 | 13.60 | 16.47 | 13.98 | -21.34 | 3.98 | -- |
| Halozyme Therapeutics, Inc. | 873.30m | 337.29m | 7.89bn | 373.00 | 24.16 | 27.24 | 18.83 | 9.04 | 2.58 | 2.58 | 6.68 | 2.29 | 0.4621 | 1.20 | 3.79 | 2,341,298.00 | 17.85 | 18.22 | 19.11 | 21.97 | 79.95 | 79.05 | 38.62 | 39.36 | 6.21 | -- | 0.8385 | 0.00 | 25.62 | 40.43 | 39.31 | -- | 26.82 | -- |
| Tempus AI Inc | 595.57m | -790.20m | 7.92bn | 2.30k | -- | 80.59 | -- | 13.29 | -8.23 | -8.23 | 4.34 | 0.6367 | -- | -- | -- | -- | -- | -- | -- | -- | 51.85 | -- | -121.04 | -- | 3.52 | -28.75 | 0.8183 | -- | 65.85 | -- | 20.35 | -- | -- | -- |
Data as of Sep 19 2024. Currency figures normalised to Ionis Pharmaceuticals Inc's reporting currency: US Dollar USD
58.49%Per cent of shares held by top holders
| Holder | Shares | % Held |
|---|---|---|
| Fidelity Management & Research Co. LLCas of 30 Jun 2024 | 21.89m | 14.98% |
| The Vanguard Group, Inc.as of 30 Jun 2024 | 13.63m | 9.32% |
| T. Rowe Price Investment Management, Inc.as of 30 Jun 2024 | 12.64m | 8.65% |
| Bellevue Asset Management AGas of 30 Jun 2024 | 8.26m | 5.65% |
| BlackRock Fund Advisorsas of 30 Jun 2024 | 7.97m | 5.45% |
| Wellington Management Co. LLPas of 30 Jun 2024 | 6.50m | 4.45% |
| SSgA Funds Management, Inc.as of 30 Jun 2024 | 4.19m | 2.87% |
| T. Rowe Price Associates, Inc. (Investment Management)as of 30 Jun 2024 | 3.79m | 2.59% |
| Tweedy, Browne Co. LLCas of 30 Jun 2024 | 3.45m | 2.36% |
| BVF Partners LPas of 30 Jun 2024 | 3.19m | 2.18% |
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Data from 30 Jun 2024 - 30 Jun 2024Source: FactSet Research Systems Inc.
